In adults with:

• Lower respiratory tract infections due to Gram-negative bacteria: exacerbations of chronic obstructive pulmonary disease, broncho-pulmonary infections in cystic fibrosis or in bronchiectasis, pneumonia.
•  Chronic suppurative otitis media.
• Acute exacerbation of chronic sinusitis especially if these are caused by Gram-negative bacteria
•  Urinary tract infections
•  Genital tract infections: gonococcal uretritis and cervicitis due to susceptible Neisseria gonorrhoeae, epididymo-orchitis including cases due to susceptible Neisseria gonorrhoeae and pelvic inflammatory disease including cases due to susceptible Neisseria gonorrhoeae.
•  Infections of the gastro intestinal tract (e.g. travellers’ diarrhea)
•  Intra-abdominal infections
•  Infections of the skin and soft tissue caused by Gram-negative bacteria
•  Malignant external otitis
•  Infections of the bones and joints
•  Prophylaxis of invasive infections due to Neisseria meningitidis
•  Inhalation anthrax (post-exposure prophylaxis and curative treatment)
•  Typhoid fever caused by Salmonella typhi.
  May be used in the management of neutropenic patients with fever that is suspected to be due to a bacterial infection.

Indicated in children and adolescents with:

• Broncho-pulmonary i nfections in cystic fibrosis caused by Pseudomonas aeruginosa
• Complicated urinary tract infections and pyelonephritis
• Inhalation anthrax (post-exposure prophylaxis and curative treatment)