For treatment of infections due to susceptible organisms. Such infections include:

• Lower respiratory tract infections (e.g., bronchitis, pneumonia)
• Upper respiratory tract infections (e.g. pharyngitis, sinusitis, tonsillitis)
• Acute otitis media in children
• Skin and soft tissue infections (e.g., folliculitis, cellulitis, erysipelas, impetigo, abscesses)
• Disseminated or localized mycobacterial infections due to MAC.
•  To eradicate Helicobacter pylori in treatment regimens for peptic ulcer disease.
• To prevent disseminated Mycobacterium avium complex (MAC) disease in patients with advanced HIV infection.
• As an alternative treatment to penicillins for prophylaxis of endocarditis.