For treatment of the following infections caused by susceptible strains:

• Lower respiratory tract infections (bronchitis, pneumonia)

• Upper respiratory tract infections (pharyngitis, sinusitis, tonsillitis)

• Acute media otitis in children.

• Skin and soft tissue infections (folliculitis, cellulitis, erysipelas).

• Leprosy.

• Disseminated or localized mycobacterial infections due to Mycobacterium avium or Mycobacterium intracellulare, Mycobacterium chelonae, Mycobacterium fortuitum, or Mycobacterium kansasii.

• Alternate to penicillins for prophylaxis of endocarditis.

• Eradicate Helicobacter pylori in treatment regimens for peptic ulcer disease.

• Tablet and granule syrup preparations are indicated for the prevention of disseminated Mycobacterium avium complex (MAC) disease in patients with advance HIV infection.

• It has been tried in protozoa infections including Toxoplasmosis.