For the treatment of:

Hemorrhage or risk of hemorrhage in increased fibrinolysis or fibrinogenolysis. Local fibrinolysis may occur in the following conditions:

• Prostatectomy and bladder surgery
• Menorrhagia
• Epistaxis
• Conisation of the cervix
• Management of dental extraction in patients with coagulopathies
• Ulcerative colitis
• Hematuria
• Gastrointestinal hemorrhage.

General fibrinolysis as in prostatic and pancreatic cancer; after thoracic and other major surgery:

• in obstetrical complications such as abruptio placentae and post-partum hemorrhage
• in leukemia and liver diseases and in connection with thrombolytic therapy with streptokinase

Hereditary angioneurotic oedema:

• For the reduction of peri- and post-operative blood loss and the need for blood transfusion in
  adult patients undergoing cardiac surgery or total knee arthroplasty or total hip arthroplasty.
• For the reduction of peri- and post-operative blood loss and the need for blood transfusion in
  pediatric patients undergoing cardiac surgery.