For the treatment of Gastro-esophageal reflux; gastric and duodenal ulcer; treatment and prophylaxis of NSAID associated ulceration; Zollinger-Ellison syndrome; Prophylaxis of acid aspiration, dyspepsia.

Indicated for the treatment of Heart burn and other symptoms associated with GERD; short term treatment of erosive esophagitis; short term treatment of active duodenal ulcer; short term treatment of active benign gastric ulcer; for reduction treatment of risk of upper gastrointestinal bleeding in critically ill patients.