Therapeutic Segment: Anti-Diabetic
Generic Name: Vildagliptin
For the treatment of type 2 diabetes mellitus in adults:
• As monotherapy in patients inadequately controlled by diet and exercise alone and for whom metformin is inappropriate due to contraindications or intolerance.
• As dual oral therapy in combination with:
• Metformin, in patients with insufficient glycemic control despite maximal tolerated dose of
monotherapy with Metformin.
• Sulfonylurea, in patients with insufficient glycemic control despite maximal tolerated dose of a
sulfonylurea and for whom metformin is inappropriate due to contraindications or intolerance.
• Thiazolidinedione, in patients with insufficient glycemic control and for
whom the use of a thiazolidinedione is appropriate.
• As triple oral therapy in combination with Sulfonylurea and Metformin when diet and exercise plus dual therapy with these medicinal products do not provide adequate glycemic control.
Also indicated for use in combination with insulin (with or without metformin) when diet and exercise plus a stable dose of insulin do not provide adequate glycemic control.
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