Zoldap™ (Linezolid) is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below. Zoldap™ (Linezolid) is not indicated for the treatment of Gram-negative infections. It is critical that specific Gram-negative therapy be initiated immediately if a concomitant Gram-negative pathogen is documented or suspected.

Pneumonia

• Nosocomial pneumonia caused by Staphylococcus aureus (methicillin-susceptible and resistant isolates) or Streptococcus pneumoniae.
• Community-acquired pneumonia caused by Streptococcus pneumoniae, including cases with concurrent bacteremia or Staphylococcus aureus (methicillin-susceptible isolates).

Skin and Skin Structure Infections

• Complicated skin and skin structure infections, including diabetic foot infections, without concomitant osteomyelitis caused by Staphylococcus aureus (methicillin-susceptible and resistant isolates), Streptococcus pyogenes or Streptococcus agalactiae.
• Uncomplicated skin and skin structure infections caused by Staphylococcus aureus (methicillin-susceptible isolates only) or Streptococcus pyogenes.

Vancomycin-resistant Enterococcus faecium Infections

• Vancomycin-resistant Enterococcus faecium infections, including cases with concurrent bacteremia.